Comparison

Anti-KIR2DS4 Antibody

€203.00
Excl. VAT
Item no. STJ26179-50
Manufacturer St John's Laboratory
Amount 50ul
Category
Type Antibody
Applications WB, IF
Specific against Human (Homo sapiens)
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Available
Description
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.
Short Description
Rabbit polyclonal to KIR2DS4
Alternative names
KIR2DS4 antibody
Killer cell immunoglobulin-like receptor 2DS4 antibody
CD158 antigen-like family member I antibody
MHC class I NK cell receptor antibody
Natural killer-associated transcript 8 antibody
NKAT-8 antibody
P58 natural killer cell receptor clones CL-39/CL-17 antibody
p58 NK receptor CL-39/CL-17 antibody
CD antigen CD158i antibody
KIR2DS4 antibody
CD158I antibody
KKA3 antibody
NKAT8 antibody
Clonality
Polyclonal
Conjugation
Unconjugated
Dilution range
WB 1:500 - 1:2000
IF 1:50 - 1:200
Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Gene id
Gene symbol
Immunogen
Recombinant protein of human KIR2DS4
Iso type
IgG
Molecular weight
33.583 kDa
Note
For Research Use Only (RUO).
Purification
Affinity purification
Storage instruction
Store at -20C. Avoid freeze / thaw cycles.
Swiss prot key
Uniprot id
P43632

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50ul
Available: In stock
Listprice: €203.00
Price: €203.00
available

Delivery expected until 8/7/2025 

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