Anti-CYBB antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

P04839

Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.

CYBB

Rabbit polyclonal against CYBB

Cell Membrane
Multi-Pass Membrane Protein
As Unassembled Monomer May Localize To The Endoplasmic Reticulum

WB 1:500-1:2000

Cytochrome B-245 Heavy Chain
Cgd91-Phox
Cytochrome B(558 Subunit Beta
Cytochrome B558 Subunit Beta
Heme-Binding Membrane Glycoprotein Gp91phox
Nadph Oxidase 2
Neutrophil Cytochrome B 91 Kda Polypeptide
Superoxide-Generating Nadph Oxidase Heavy Chain Subunit
Gp91-1
Gp91-Phox
P22 Phagocyte B-Cytochrome

CY24B_HUMAN