Anti-CYBB antibody

203,00 €

Zzgl. MwSt.

ArtNr	STJ114304-50
Hersteller	St John's Laboratory
Menge	50ul
Kategorie	Neuroscience Molecular Targets for Neuroscience Antibodies Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Anti-Cytochrome B-245 Heavy Chain antibody</br>Anti-Cgd91-Phox antibody</br>Anti-Cytochrome B(558 Subunit Beta antibody</br>Anti-Cytochrome B558 Subunit Beta antibody</br>Anti-Heme-Binding Membrane Glycoprotein Gp91phox antibody</br>Anti-Nadph Oxidase 2 a
Similar products	Anti-Cytochrome B-245 Heavy Chain antibody Anti-Cgd91-Phox antibody Anti-Cytochrome B(558 Subunit Beta antibody Anti-Cytochrome B558 Subunit Beta antibody Anti-Heme-Binding Membrane Glycoprotein Gp91phox antibody Anti-Nadph Oxidase 2 a
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Clonality	Polyclonal
Conjugation	Unconjugated
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification	Affinity purification
Uniprot ID	P04839
Storage	Store at-20° C and avoid freeze-thaw cycles.
Description	Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.
Gene ID	1536
Gene symbol	CYBB
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CYBB (NP_000388. 2).
Short Description	Rabbit polyclonal against CYBB
Tissue specificity	Detected in neutrophils (at protein level).
Cellular localization	Cell Membrane Multi-Pass Membrane Protein As Unassembled Monomer May Localize To The Endoplasmic Reticulum
Molecular weight	Calculated: 65kDa. Observed: 58kDa/72kDa
Dilution range	WB 1:500-1:2000
Alternative names	Anti-Cytochrome B-245 Heavy Chain antibody Anti-Cgd91-Phox antibody Anti-Cytochrome B(558 Subunit Beta antibody Anti-Cytochrome B558 Subunit Beta antibody Anti-Heme-Binding Membrane Glycoprotein Gp91phox antibody Anti-Nadph Oxidase 2 antibody Anti-Neutrophil Cytochrome B 91 Kda Polypeptide antibody Anti-Superoxide-Generating Nadph Oxidase Heavy Chain Subunit antibody Anti-Gp91-1 antibody Anti-Gp91-Phox antibody Anti-P22 Phagocyte B-Cytochrome antibody Anti-CYBB NOX2 antibody
Protein name	Cytochrome B-245 Heavy Chain Cgd91-Phox Cytochrome B(558 Subunit Beta Cytochrome B558 Subunit Beta Heme-Binding Membrane Glycoprotein Gp91phox Nadph Oxidase 2 Neutrophil Cytochrome B 91 Kda Polypeptide Superoxide-Generating Nadph Oxidase Heavy Chain Subunit Gp91-1 Gp91-Phox P22 Phagocyte B-Cytochrome
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	CY24B_HUMAN

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Menge: 50ul

Listenpreis: 203,00 €

Preis: 203,00 €

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