BAFF

€127.00

Excl. VAT

Item no.	RLT-100-002S
Manufacturer	ReliaTech
Amount	5ug
Category	Oncology By Cell Type Hematology Leukemia Lymphoma Sarcoma Peptides & Proteins Recombinant Proteins Myelofibrosis
Type	Cytokines and Growth Factors
Format	Lyophilized
Specific against	Human (Homo sapiens)
Host	E.coli
ECLASS 10.1	42030690
ECLASS 11.0	42030690
UNSPSC	12352202
Alias	TNFSF13B, DTL, BAFF, BLYS, CD257, TALL1, THANK, ZTNF4, TALL-1, TNFSF20
Available
NCBI Gene ID	10673
Uniprot	Q9Y275
Biological Activity	Determined by its dose-dependent stimulation of IL-8 production by human PBMC. The ED50 for this effect is less than 10 ng/ml.
Buffer	0.5 x PBS pH 7.5 + 0.5 mM DTT
Description	BAFF, a member of the TNF family of ligands, is expressed in T cells, macrophages, monocytes and dendritic cells. BAFF is involved in stimulation of B and T cell function, and is an important survival and maturation factor for peripheral B cells. BAFF signals through three different TNF receptors TACI, BCMA and BAFF-R. The human BAFF gene codes for a 285 amino acid type II transmembrane protein containing a 46 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a 218 amino acid extracellular domain. Recombinant human soluble BAFF is a 153 amino acid polypeptide (17.0 kDa), which contains the TNF-like portion of the extracellular domain of BAFF.
Endotoxin Levels	< 0.1 ng/µg of protein (<1EU/µg)
Length [aa]	153
Molecular Weight	17.0 kDa
mRNA RefSeq	NM_006573.4
Protein RefSeq	NP_006564.1
Protein Sequence	AVQGPEETVTQDCLQLIADSETPTIQKGSYTFVPWLLSFKRGSALEEKENKILVKETGYFFIYGQVLYTKTYAMGHLIQRKKVHVFGDELSLVTLFRCIQNMPETLPNNSCYSAGIAKLEEGDELQLAIPRENAQISLDGDVTFFGALKLL
Purity Confirmation	> 98% by SDS-PAGE & HPLC analyses
Synonyms	TNFSF13B; DTL; BAFF; BLYS; CD257; TALL1; THANK; ZTNF4; TALL-1; TNFSF20
Uniprot ID	Q9Y275

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Amount: 5ug

Listprice: €127.00

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