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Recombinant Human LAG3 Protein

Recombinant Human LAG3 Protein

€330.00

Excl. VAT

Item no.	RP02055-100ug
Manufacturer	Abclonal
Amount	100 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	Human (Homo sapiens)
Host	Human
Purity	> 95% by SDS-PAGE.
NCBI	LAG-3/CD223
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Available
Description	Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.
Background	LAG-3, is a protein which in humans is encoded by the LAG3 gene, which is a cell surface molecule with diverse biologic effects on T cell function. It is an immune checkpoint receptor and as such is the target of various drug development programs by pharmaceutical companies seeking to develop new treatments for cancer and autoimmune disorders.
Route	C-hFc
Manufacturers Category	Proteins
Endotoxin	< 0.1 EU/μg of the protein by LAL method.
Immunogen	Leu23-Gly450
Storage	Store the lyophilized protein at -20°C to -80 °C for long term. After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
Manufacturers Research Area	Immune Checkpoint, Bio-Markers & CD Antigens, Biosimilar Drug Targets
Gene Symbol	LAG-3/CD223
Protein Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation.
Protein Description	Recombinant Mouse CD40L/CD154 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Leu23-Gly450) of human LAG3 (Accession #P18627) fused with an Fc tag at the C-terminus.
Protein Bio Activity	Immobilized Human FGL1 at 2 μg/mL (100 μL/well), dose response curve for Human LAG3, Fc with the EC₅₀ of 21 ng/mL determined by ELISA.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

Listprice: €330.00

Price: €330.00

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Delivery expected until 9/30/2025

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