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LAG-3 Recombinant Protein

LAG-3 Recombinant Protein

€678.00

Excl. VAT

Item no.	PRS-90-241-50ug
Manufacturer	ProSci
Amount	50 ug
Category	Neuroscience Aging & Neurological Disorders Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Liquid
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Lymphocyte Activation Gene-3, FDC Protein, CD223
Available
Applications	This recombinant proteins is for research use only.
Applications	This recombinant proteins is for research use only.
Buffer	In PBS.
Storage Conditions	Stable for at least 6 months after receipt when stored at -20˚ C.
Disclaimer	Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Purity	>99% (SDS-PAGE). Endotoxin level is less than 0.1EU/ μ g purified protein (LAL test; Lonza).
Background	Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.
Concentration	0.5 mg/ml
Accession #	P18627
Ncbi Gene Id #	3902
Ncbi Official Symbol	LAG3
Ncbi Official Full Name	lymphocyte activating 3
Ncbi Organism	Homo sapiens
Swissprot #	O95631
Fusion Tag	Fc Tag
Sequence	The sequence coding for the 4 extracellular Ig-like domains of human LAG-3 (D1-D4) is fused to the Fc portion of human IgG1.
Biological Activity	Inhibits binding of MAb to LAG-3 (human) to LAG-3. Induces maturation of human dendritic cells.
Protein Gi#	251757512

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

Listprice: €678.00

Price: €678.00

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Delivery expected until 9/4/2025

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