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LAG-3 Recombinant Protein

678,00 €
Zzgl. MwSt.
ArtNr PRS-90-241-50ug
Hersteller ProSci
Menge 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Specific against other
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Lymphocyte Activation Gene-3, FDC Protein, CD223
Lieferbar
Applications
This recombinant proteins is for research use only.
Applications
This recombinant proteins is for research use only.
Buffer
In PBS.
Storage Conditions
Stable for at least 6 months after receipt when stored at -20˚ C.
Disclaimer
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Purity
>99% (SDS-PAGE).

Endotoxin level is less than 0.1EU/ μ g purified protein (LAL test; Lonza).
Background
Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.
Concentration
0.5 mg/ml
Accession #
P18627
Ncbi Gene Id #
3902
Ncbi Official Symbol
LAG3
Ncbi Official Full Name
lymphocyte activating 3
Ncbi Organism
Homo sapiens
Swissprot #
O95631
Fusion Tag
Fc Tag
Sequence
The sequence coding for the 4 extracellular Ig-like domains of human LAG-3 (D1-D4) is fused to the Fc portion of human IgG1.
Biological Activity
Inhibits binding of MAb to LAG-3 (human) to LAG-3. Induces maturation of human dendritic cells.
Protein Gi#
251757512

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
Listenpreis: 678,00 €
Preis: 678,00 €
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Lieferung vsl. bis 04.09.2025 

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