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Human CD3 epsilon&CD3 gamma Heterodimer Protein, Fc Tag&Fc Tag (MALS verified)

Human CD3 epsilon&CD3 gamma Heterodimer Protein, Fc Tag&Fc Tag (MALS verified)

€2,645.00

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Item no.	CDG-H5253-1mg
Manufacturer	ACROBiosystems
Amount	1mg
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Powder
Specific against	Human (Homo sapiens)
Host	HEK293
Conjugate/Tag	Fc
Purity	>95% as determined by SDS-PAGE.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CD3 epsilon & CD3 gamma,CD3E & CD3G
Available
Bioactivity Legend 1	Immobilized Human CD3E&CD3G Heterodimer Protein, Fc Tag&Fc Tag (Cat. No. CDG-H5253) at 1 ug/mL (100 uL/well) can bind Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a (Clone: OKT3), Ultra-low endotoxin (Cat. No. CDE-M120a) with a linear range of 0.8-3 ng/mL (QC tested).
Bioactivity Legend 2	Immobilized Human CD3E&CD3G Heterodimer Protein, Fc Tag&Fc Tag (Cat. No. CDG-H5253) at 1 ug/mL (100 uL/well) can bind Mouse Anti Human CD3 with a linear range of 0.8-2 ng/mL (Routinely tested).
Buffer	PBS, pH7.4
Characteristics	Human CD3E&CD3G Heterodimer Protein, Fc Tag&Fc Tag is produced by co-expression of CD3E and CD3G, has a calculated MW of 38.3 kDa (CD3E) and 36.9 kDa (CD3G). Subunit CD3E is fused with a human IgG1 Fc tag at the C-terminus and subunit CD3G is fused with a human IgG1 Fc tag at the C-terminus. As a result of glycosylation, the protein migrates as 43-55 kDa under reducing (R) condition, and 90-110 kDa under non-reducing (NR) condition (SDS-PAGE).
Description	T-cell surface glycoprotein CD3 delta & CD3 gamma chain, also known as CD3D & CD3G or CD3D&CD3G respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
Endotoxin Level	Less than 1.0 EU per ug by the LAL method.
Exp Region	Asp 23 - Asp 126 (CD3E) & Gln 23 - Ser 116 (CD3G)
Expression System	HEK293
Molecular Weight	38.3 kDa (CD3E) & 36.9 (CD3G)
Molecule	CD3E & CD3G
SDS-PAGE Legend	Human CD3E&CD3G Heterodimer Protein, Fc Tag&Fc Tag on SDS-PAGE under reducing (R) and non-reducing (NR) conditions. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Storage	-20C
Host Information	Human CD3E&CD3G Heterodimer Protein, Fc Tag&Fc Tag (CDG-H5253) is expressed from human 293 cells (HEK293). It contains AA Asp 23 - Asp 126 (CD3E) & Gln 23 - Ser 116 (CD3G) (Accession # NP_000724.1 (CD3E) & AAI13831 (CD3G)).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1mg

Listprice: €2,645.00

Price: €2,645.00

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Delivery expected until 9/11/2025

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