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Human CD3 epsilon&CD3 gamma Heterodimer Protein, Fc Tag&Fc Tag (MALS verified)

Human CD3 epsilon&CD3 gamma Heterodimer Protein, Fc Tag&Fc Tag (MALS verified)

2.645,00 €

Zzgl. MwSt.

ArtNr	CDG-H5253-1mg
Hersteller	ACROBiosystems
Menge	1mg
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Powder
Specific against	Human (Homo sapiens)
Host	HEK293
Konjugat/Tag	Fc
Purity	>95% as determined by SDS-PAGE.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CD3 epsilon & CD3 gamma,CD3E & CD3G
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Bioactivity Legend 1	Immobilized Human CD3E&CD3G Heterodimer Protein, Fc Tag&Fc Tag (Cat. No. CDG-H5253) at 1 ug/mL (100 uL/well) can bind Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a (Clone: OKT3), Ultra-low endotoxin (Cat. No. CDE-M120a) with a linear range of 0.8-3 ng/mL (QC tested).
Bioactivity Legend 2	Immobilized Human CD3E&CD3G Heterodimer Protein, Fc Tag&Fc Tag (Cat. No. CDG-H5253) at 1 ug/mL (100 uL/well) can bind Mouse Anti Human CD3 with a linear range of 0.8-2 ng/mL (Routinely tested).
Buffer	PBS, pH7.4
Characteristics	Human CD3E&CD3G Heterodimer Protein, Fc Tag&Fc Tag is produced by co-expression of CD3E and CD3G, has a calculated MW of 38.3 kDa (CD3E) and 36.9 kDa (CD3G). Subunit CD3E is fused with a human IgG1 Fc tag at the C-terminus and subunit CD3G is fused with a human IgG1 Fc tag at the C-terminus. As a result of glycosylation, the protein migrates as 43-55 kDa under reducing (R) condition, and 90-110 kDa under non-reducing (NR) condition (SDS-PAGE).
Description	T-cell surface glycoprotein CD3 delta & CD3 gamma chain, also known as CD3D & CD3G or CD3D&CD3G respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
Endotoxin Level	Less than 1.0 EU per ug by the LAL method.
Exp Region	Asp 23 - Asp 126 (CD3E) & Gln 23 - Ser 116 (CD3G)
Expression System	HEK293
Molecular Weight	38.3 kDa (CD3E) & 36.9 (CD3G)
Molecule	CD3E & CD3G
SDS-PAGE Legend	Human CD3E&CD3G Heterodimer Protein, Fc Tag&Fc Tag on SDS-PAGE under reducing (R) and non-reducing (NR) conditions. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Storage	-20C
Host Information	Human CD3E&CD3G Heterodimer Protein, Fc Tag&Fc Tag (CDG-H5253) is expressed from human 293 cells (HEK293). It contains AA Asp 23 - Asp 126 (CD3E) & Gln 23 - Ser 116 (CD3G) (Accession # NP_000724.1 (CD3E) & AAI13831 (CD3G)).

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Menge: 1mg

Listenpreis: 2.645,00 €

Preis: 2.645,00 €

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Lieferung vsl. bis 11.09.2025

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