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Berbamine dihydrochloride

Berbamine dihydrochloride

€43.00

Excl. VAT

Item no.	HY-N0714A-10mM
Manufacturer	MedChem Express
CASRN	6078-17-7
Amount	10 mM/1 mL
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Lung Cancer
Type	Inhibitors
Specific against	other
Purity	96.62
Formula	C37H42Cl2N2O6
Citations	Cell Stress Chaperones. 2021 Jan 6. J Ethnopharmacol. 2022 Dec 7;303:116025. Patent. US20220017867A1. Chemrxiv. Oct 12, 2021. Drug Des Devel Ther. 2022 Jan 11;16:129-141. Mol Pharm. 2022 Oct 21. PLoS Pathog. 2023 Jan 26;19(1):e1011131. [1]Liang Y, et al. Berbamine, a novel nuclear factor kappaB inhibitor, inhibits growth and induces apoptosis in human myeloma cells. Acta Pharmacol Sin. 2009 Dec;30(12):1659-65. [2]Meng Z, et al. Berbamine inhibits the growth of liver cancer cells and cancer-initiating cells by targeting Ca<sup>2+</sup>/calmodulin-dependent protein kinase II. Mol Cancer Ther. 2013 Oct;12(10):2067-77.
Smiles	COC1=C(OC2=CC([C@]3([H])CC(C=C4)=CC=C4O5)=C(CCN3C)C=C2OC)C([C@@]6([H])CC7=CC=C(O)C5=C7)=C(CCN6C)C=C1OC.Cl.Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	6078-17-7
Available
Product Description	Berbamine dihydrochloride is an inhibitor of NF-κB activity with remarkable anti-myeloma efficacy.
StorageTemperature	4°C (Powder, sealed storage, away from moisture)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
Molecular Weight	681.65
Clinical Information	Launched
Solubility	DMSO : ≥ 100 mg/mL
Isoform	NF-κB
Pathway	Apoptosis; Autophagy; NF-κB
Manufacturers Product type	Natural Products

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HY-N0714A-10mM-safety-datasheet.pdf