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Omadacycline hydrochloride

Omadacycline hydrochloride

€307.00

Excl. VAT

Item no.	HY-14865C-5mg
Manufacturer	MedChem Express
CASRN	1196800-39-1
Amount	5 mg
Category	Oncology Food Safety Antibiotics Neuroscience Neural Lineage Markers By Cell Type Blastoma Carcinoma Sarcoma Cell Biology Cell Status Cytoskeleton Proliferation Inhibitors & Compound Libraries Small Molecules Intermediate filaments By Organ Bladder Cancer Breast Cancer
Type	Inhibitors
Purity	99.87
Formula	C29H40N4O7.HCl
Citations	J Antimicrob Chemother. 2021 Feb 11;76(3):653-658. J Antimicrob Chemother. 2021 May 6;dkab141. Virulence. 2022 Dec;13(1):77-88. Animal Feed Science and Technology. 2014 Dec;198:323-332. Ann Lab Med. 2021 May 1;41(3):293-301. Antibiotics (Basel). 2022, 11(10), 1298. Antimicrob Agents Chemother. 2019 May 24;63(6). pii: e00470-19. Antimicrob Agents Chemother. 2020 Feb 21;64(3):e02097-19. Antimicrob Agents Chemother. 2023 Jan 23;e0145922. Clin Exp Pharmacol Physiol. 2023 Apr 22. Comput Intell Neurosci. 2022 Apr 25;2022:7636983. Diagn Micr Infec Dis. 2020 Nov;98(3):115129. J Antibiot (Tokyo). 2022 Jun 27. J Clin Microbiol. 2020 Jan 28;58(2):e01603-19. Microbiol Spectr. 2022 Dec 8;e0323822. Microbiol Spectr. 2023 May 4;e0071823. Nat Microbiol. 2023 Mar;8(3):410-423. Nat Struct Mol Biol. 2023 Aug 7. PLoS Biol. 2022 Sep 28;20(9):e3001808. Research Square Preprint. 2020 Jun. [1]Zhanel GG, et, al. Omadacycline: A Novel Oral and Intravenous Aminomethylcycline Antibiotic Agent. Drugs. 2020 Feb;80(3):285-313. [2]Markham A, et, al. Omadacycline: First Global Approval. Drugs. 2018 Dec;78(18):1931-1937. [3]Macone AB, et, al. In vitro and in vivo antibacterial activities of omadacycline, a novel aminomethylcycline. Antimicrob Agents Chemother. 2014;58(2):1127-35. [4]Durães F, et, al. Omadacycline: A Newly Approved Antibacterial from the Class of Tetracyclines. Pharmaceuticals (Basel). 2019 Apr 21;12(2):63.
Smiles	O=C(C1=C(O)[C@@H](N(C)C)[C@@](C[C@@]2([H])C(C(C3=C(O)C(CNCC(C)(C)C)=CC(N(C)C)=C3C2)=O)=C4O)([H])[C@@]4(O)C1=O)N.Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	PTK0796 hydrochloride; Amadacycline hydrochloride
Available
Product Description	Omadacycline (PTK 0796) hydrochloride, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline hydrochloride acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline hydrochloride possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline hydrochloride can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections[1][2][3][4].
StorageTemperature	-20°C (Powder, sealed storage, away from moisture)
Shipping	Blue Ice
Manufacturers Applications	COVID-19-immunoregulation
Molecular Weight	593.11
Clinical Information	Launched
Solubility	DMSO : 50 mg/mL (ultrasonic)\|H2O : 200 mg/mL (ultrasonic)
Isoform	Tetracycline
Pathway	Anti-infection
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-14865C-5mg-safety-datasheet.pdf