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Omadacycline hydrochloride

Omadacycline hydrochloride

307,00 €

Zzgl. MwSt.

ArtNr	HY-14865C-5mg
Hersteller	MedChem Express
CAS-Nr.	1196800-39-1
Menge	5 mg
Kategorie	Oncology Food Safety Antibiotics Neuroscience Neural Lineage Markers By Cell Type Blastoma Carcinoma Sarcoma Cell Biology Cell Status Cytoskeleton Proliferation Inhibitors & Compound Libraries Small Molecules Intermediate filaments By Organ Bladder Cancer Breast Cancer
Typ	Inhibitors
Purity	99.87
Formula	C29H40N4O7.HCl
Citations	J Antimicrob Chemother. 2021 Feb 11;76(3):653-658. J Antimicrob Chemother. 2021 May 6;dkab141. Virulence. 2022 Dec;13(1):77-88. Animal Feed Science and Technology. 2014 Dec;198:323-332. Ann Lab Med. 2021 May 1;41(3):293-301. Antibiotics (Basel). 2022, 11(10), 1298. Antimicrob Agents Chemother. 2019 May 24;63(6). pii: e00470-19. Antimicrob Agents Chemother. 2020 Feb 21;64(3):e02097-19. Antimicrob Agents Chemother. 2023 Jan 23;e0145922. Clin Exp Pharmacol Physiol. 2023 Apr 22. Comput Intell Neurosci. 2022 Apr 25;2022:7636983. Diagn Micr Infec Dis. 2020 Nov;98(3):115129. J Antibiot (Tokyo). 2022 Jun 27. J Clin Microbiol. 2020 Jan 28;58(2):e01603-19. Microbiol Spectr. 2022 Dec 8;e0323822. Microbiol Spectr. 2023 May 4;e0071823. Nat Microbiol. 2023 Mar;8(3):410-423. Nat Struct Mol Biol. 2023 Aug 7. PLoS Biol. 2022 Sep 28;20(9):e3001808. Research Square Preprint. 2020 Jun. [1]Zhanel GG, et, al. Omadacycline: A Novel Oral and Intravenous Aminomethylcycline Antibiotic Agent. Drugs. 2020 Feb;80(3):285-313. [2]Markham A, et, al. Omadacycline: First Global Approval. Drugs. 2018 Dec;78(18):1931-1937. [3]Macone AB, et, al. In vitro and in vivo antibacterial activities of omadacycline, a novel aminomethylcycline. Antimicrob Agents Chemother. 2014;58(2):1127-35. [4]Durães F, et, al. Omadacycline: A Newly Approved Antibacterial from the Class of Tetracyclines. Pharmaceuticals (Basel). 2019 Apr 21;12(2):63.
Smiles	O=C(C1=C(O)[C@@H](N(C)C)[C@@](C[C@@]2([H])C(C(C3=C(O)C(CNCC(C)(C)C)=CC(N(C)C)=C3C2)=O)=C4O)([H])[C@@]4(O)C1=O)N.Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	PTK0796 hydrochloride; Amadacycline hydrochloride
Lieferbar
Product Description	Omadacycline (PTK 0796) hydrochloride, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline hydrochloride acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline hydrochloride possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline hydrochloride can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections[1][2][3][4].
StorageTemperature	-20°C (Powder, sealed storage, away from moisture)
Shipping	Blue Ice
Manufacturers Applications	COVID-19-immunoregulation
Molecular Weight	593.11
Clinical Information	Launched
Solubility	DMSO : 50 mg/mL (ultrasonic)\|H2O : 200 mg/mL (ultrasonic)
Isoform	Tetracycline
Pathway	Anti-infection
Manufacturers Product type	Reference compound

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HY-14865C-5mg-safety-datasheet.pdf