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BIO8898

BIO8898

€807.00

Excl. VAT

Item no.	HY-122663A-5mg
Manufacturer	MedChem Express
Amount	5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	99.88
Formula	C53H64N8O6
Citations	[1]Silvian LF, et al. Small molecule inhibition of the TNF family cytokine CD40 ligand through a subunit fracture mechanism. ACS Chem Biol. 2011 Jun 17;6(6):636-47.
Smiles	O=C(O)[C@@H](NC(C1=NC(C(N2[C@H](CN3CCCC3)CCC2)=O)=CC(C4=CC(C(NCC5=CC(C6=CC=CC=C6)=CC=C5)=O)=NC(C(N7[C@H](CN8CCCC8)CCC7)=O)=C4)=C1)=O)C9CCCCC9
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	BIO8898 is a potent CD40-CD154 inhibitor. BIO8898 inhibits soluble CD40L binding to CD40-Ig with an IC50 value of 25 µM. BIO8898 inhibits CD40L-induced apoptosis[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Metabolism-protein/nucleotide metabolism
Molecular Weight	909.13
Clinical Information	No Development Reported
Solubility	DMSO : 50 mg/mL (ultrasonic)
Isoform	TNFRSF5/CD40
Pathway	Apoptosis
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5 mg

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