Native Human Cathepsin G

€571.00

Excl. VAT

Item no.	CS-CSI19629A
Manufacturer	Cell Sciences
Amount	1.0 mg
Category	Oncology Peptides & Proteins Cell Biology Cell Status Apoptosis By Organ Testicular & Prostate Cancer Native Proteins
Type	Proteins
Purity	>96% by SDS-PAGE
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Available
Biological Activity	One unit will hydrolyze one micromole of Succinyl-alanine-alanine-propline-phenylalanine-p-nitroanilide per minute at 37C and pH 7.5
Concentration	Typically >0.25 mg/mL
Description	Human Cathepsin G (CTSG) is a serine protease, and a member of the peptidase S1 protein family, located in the azurophil granules of neutrophils. Studies have shown that CTSG when released from granulocytes binds to NK cells and augments NK cytotoxicity through its protease activity. CTSG has a specificity similar to that of Chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. Transcript variants utilizing alternative polyadenylation signals exist for this gene.
Formulation	Sterile (0.2 um) filtered liquid in 50 mM Sodium Acetate, pH 5.5 + 0.8 M NaCl
Storage and Stability	Store at 2-4C. 1 year.

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