Native Human Cathepsin G

One unit will hydrolyze one micromole of Succinyl-alanine-alanine-propline-phenylalanine-p-nitroanilide per minute at 37C and pH 7.5

Human Cathepsin G (CTSG) is a serine protease, and a member of the peptidase S1 protein family, located in the azurophil granules of neutrophils. Studies have shown that CTSG when released from granulocytes binds to NK cells and augments NK cytotoxicity through its protease activity. CTSG has a specificity similar to that of Chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. Transcript variants utilizing alternative polyadenylation signals exist for this gene.

Store at 2-4C. 1 year.