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MAP1LC3A polyclonal antibody

MAP1LC3A polyclonal antibody

Item no.	BS90822-50
Manufacturer	Bioworld Technology, Inc
Amount	50ul
Category	Neuroscience Neural Lineage Markers Protein Aggregation, Clearance & Misfolding Antibodies Cell Biology Cell Status Immunohistochemistry Immunoprecipitation Western Blot Immunocytochemistry Autophagy Primary Antibodies Astroglia Markers
Type	Antibody Primary
Applications	WB, IP, IHC, ICC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	MAP1A/MAP1B LC3 A, MAP1LC3A, ATG8E, Autophagy-related protein LC3 A, Autophagy-related ubiquitin-like modifier LC3 A, LC3, LC3A, MAP1 light chain 3 like protein 1, MAP1 light chain 3-like protein 1, MAP1A/1B light chain 3 A, MAP1A/MAP1B LC3 A, MAP1A/MAP1B
Available
Swiss-Prot	Q9H492(Human) Q91VR7(Mouse) Q6XVN8(Rat)
Application_all	WB:1:1, 000-1:2, 000 ICC:1:50-1:200 IHC:1:50-1:200
Background	Microtubule-associated proteins (MAPs) regulate microtubule stability and play critical roles in neuronal development and in maintaining the balance between neuronal plasticity and rigidity. MAP-light chain 3 beta (MAP-LC3beta) and MAP-light chain 3 alpha (MAP-LC3alpha), both of which are mammalian homologs of yeast Apg8, are subunits that can associate with either MAP-1A or MAP-1B. While MAP-LC3beta is essential for autophagy and is associated with autophagosome membranes after processing, MAP LC3alpha is involved in the formation of autophagosomal vacuoles and is localized to the intracytoplasmic membrane. MAP LC3alpha is expressed as two alternatively spliced isoforms that are expressed in testis, brain, heart, liver and skeletal muscle, but are absent in thymus and peripheral blood leukocytes.
Product	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification And Purity	ProA affinity purified
Storage And Stability	Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
Specificity	MAP1LC3A polyclonal antibody detects endogenous levels of MAP1LC3A protein.
BiowMW	14 kDa
Note	For research use only, not for use in diagnostic procedure.
Immunogen	recombinant protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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