MAP1LC3A polyclonal antibody

Q9H492(Human) Q91VR7(Mouse) Q6XVN8(Rat)

Microtubule-associated proteins (MAPs) regulate microtubule stability and play critical roles in neuronal development and in maintaining the balance between neuronal plasticity and rigidity. MAP-light chain 3 beta (MAP-LC3beta) and MAP-light chain 3 alpha (MAP-LC3alpha), both of which are mammalian homologs of yeast Apg8, are subunits that can associate with either MAP-1A or MAP-1B. While MAP-LC3beta is essential for autophagy and is associated with autophagosome membranes after processing, MAP LC3alpha is involved in the formation of autophagosomal vacuoles and is localized to the intracytoplasmic membrane. MAP LC3alpha is expressed as two alternatively spliced isoforms that are expressed in testis, brain, heart, liver and skeletal muscle, but are absent in thymus and peripheral blood leukocytes.

ProA affinity purified

MAP1LC3A polyclonal antibody detects endogenous levels of MAP1LC3A protein.

For research use only, not for use in diagnostic procedure.