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SARS-CoV-2 ADE-Causing Antibody (S9HC)

SARS-CoV-2 ADE-Causing Antibody (S9HC)

€375.00

Excl. VAT

Item no.	A02133-100
Manufacturer	GenScript
Amount	100 ug
Category	Antibodies Primary Antibodies
Type	Antibody
Format	Liquid
Clone	S9HC
Specific against	other
Host	Humanized
Isotype	IgG1
Conjugate/Tag	Unconjugated
Citations	[1] Liu Y, Soh W T, Kishikawa J I, et al. An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies. 2021.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Anti-SARS-CoV-2 ADE-Causing Antibody; SARS-CoV-2 Antibody-dependent enhancement Antibody; SARS-CoV-2 ADE response Antibody; SARS-CoV-2 Spike Antibody; SARS-CoV-2 ADE effect.
Available
Specificity	GenScript SARS-CoV-2 ADE-Causing Antibody (S9HC) reacts with SARS-CoV-2 Spike protein of wild type and delta variant. It can obviously enhance the SARS-COV-2 binding with ACE2.
Specificity	GenScript SARS-CoV-2 ADE-Causing Antibody (S9HC) reacts with SARS-CoV-2 Spike protein of wild type and delta variant. It can obviously enhance the SARS-COV-2 binding with ACE2.
Clonality	Monoclonal
Concentration	1 mg/ml
Endotoxin Level	< 10 EU/mg
Immunogen	SARS-CoV-2 Spike protein
Purification	Affinity chromatography
Storage Buffer	PBS, pH 7.2, Azide free
Storage Instructions	Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed. Avoid repeated freezing and thawing cycles.
Target Background	SARS-CoV-2 ADE-causing antibody is a SARS-CoV-2 Spike protein antibody that can exacerbate the COVID-19 disease severity of patients. Antibody-dependent enhancement (ADE) may be involved in the clinical observation of patients with increased severity of symptoms and high levels of SARS-CoV-2 antibodies. It is reported [1] that the same antibodies against the NTD domain of the SARS-CoV-2 spike protein have an ADE effect by increasing the binding of ACE2 to the spike protein.
Manufacturers Category	Antibodies
Manufacturers Product Line	COVID-19 Antibodies
Product Origin	USA

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

Listprice: €375.00

Price: €375.00

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Delivery expected until 9/4/2025

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