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SARS-CoV-2 ADE-Causing Antibody (S9HC)

SARS-CoV-2 ADE-Causing Antibody (S9HC)

375,00 €

Zzgl. MwSt.

ArtNr	A02133-100
Hersteller	GenScript
Menge	100 ug
Kategorie	Antibodies Primary Antibodies
Typ	Antibody
Format	Liquid
Clon	S9HC
Specific against	other
Host	Humanized
Isotype	IgG1
Konjugat/Tag	Unconjugated
Citations	[1] Liu Y, Soh W T, Kishikawa J I, et al. An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies. 2021.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Anti-SARS-CoV-2 ADE-Causing Antibody; SARS-CoV-2 Antibody-dependent enhancement Antibody; SARS-CoV-2 ADE response Antibody; SARS-CoV-2 Spike Antibody; SARS-CoV-2 ADE effect.
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Specificity	GenScript SARS-CoV-2 ADE-Causing Antibody (S9HC) reacts with SARS-CoV-2 Spike protein of wild type and delta variant. It can obviously enhance the SARS-COV-2 binding with ACE2.
Specificity	GenScript SARS-CoV-2 ADE-Causing Antibody (S9HC) reacts with SARS-CoV-2 Spike protein of wild type and delta variant. It can obviously enhance the SARS-COV-2 binding with ACE2.
Clonality	Monoclonal
Concentration	1 mg/ml
Endotoxin Level	< 10 EU/mg
Immunogen	SARS-CoV-2 Spike protein
Purification	Affinity chromatography
Storage Buffer	PBS, pH 7.2, Azide free
Storage Instructions	Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed. Avoid repeated freezing and thawing cycles.
Target Background	SARS-CoV-2 ADE-causing antibody is a SARS-CoV-2 Spike protein antibody that can exacerbate the COVID-19 disease severity of patients. Antibody-dependent enhancement (ADE) may be involved in the clinical observation of patients with increased severity of symptoms and high levels of SARS-CoV-2 antibodies. It is reported [1] that the same antibodies against the NTD domain of the SARS-CoV-2 spike protein have an ADE effect by increasing the binding of ACE2 to the spike protein.
Manufacturers Category	Antibodies
Manufacturers Product Line	COVID-19 Antibodies
Product Origin	USA

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Menge: 100 ug

Listenpreis: 375,00 €

Preis: 375,00 €

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Lieferung vsl. bis 28.08.2025

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