Goat anti-ICOS ligand / B7-H2 Antibody

Goat anti-ICOS ligand / B7-H2 Antibody
Principle Name: ICOS ligand / B7-H2
Official Symbol: ICOSLG
All Name and Symbols: ICOSLG; inducible T-cell co-stimulator ligand; B7-H2; B7H2; B7RP-1; B7RP1; CD275; GL50; ICOS-L; ICOSL; LICOS; B7 homolog 2; B7 homologue 2; B7-like protein Gl50; B7-related protein 1; ICOS ligand; transmembrane protein B7-H2 ICOS ligand
Accession Number(s): NP_056074.1; NP_001269979.1; NP_001269980.1; NP_001269981.1
Peptide Sequence: SQTGNDIGERDKIT, is from internal region
Human Gene ID(s): 23308
Non-Human GeneID(s):
Important Comments: This antibody is expected to recognize all reported isoforms (NP_056074.1; NP_001269979.1; NP_001269980.1; NP_001269981.1).
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As: lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20C. Minimize freezing and thawing.
Applications: Pep ELISA, WB
Tested Species: Human
Peptide ELISA: antibody detection limit dilution 1 to 8000.
Western Blot: Approx 33kDa band observed in Human Lymph Node lysates (calculated MW of 33.3kDa according to NP_056074.1). Recommended concentration: 1-3ug/ml.
Reference(s): Martin-Orozco N, Li Y, Wang Y, Liu S, Hwu P, Liu YJ, Dong C, Radvanyi L. Melanoma cells express ICOS ligand to promote the activation and expansion of T-regulatory cells. Cancer research 2010 Dec 70 (23): 9581-90..PMID: 21098714