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Recombinant Mouse IL-17A/CTLA-8 Protein

415,00 €
Zzgl. MwSt.
ArtNr RP02520-50ug
Hersteller Abclonal
Menge 50 ug
Kategorie
Typ Proteins Recombinant
Specific against Mouse (Murine, Mus musculus)
Purity > 98% by SDS-PAGE.
Sequence MAAIIPQSSACPNTEAKDFLQNVKVNLKVFNSLGAKVSSRRPSDYLNRSTSPWTLHRNEDPDRYPSVIWEAQCRHQRCVNAEGKLDHHMNSVLIQQEILVLKREPESCPFTFRVEKMLVGVGCTCVASIVRQAA
NCBI IL-17A/CTLA-8
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias CTLA-8,CTLA8cytotoxic T-lymphocyte-associated serine esterase 8,Cytotoxic T-lymphocyte-associated antigen 8,IL17,IL-17,IL17A,IL-17A,IL-17Acytotoxic T-lymphocyte-associated protein 8,IL-17CTLA-8,IL17interleukin-17A,interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8),interleukin 17A
Lieferbar
Description
Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.
Background
Interleukin-17A is a protein that in humans is encoded by the IL17A gene. The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO).
Route
C-His
Manufacturers Category
Proteins
Endotoxin
<0.1EU/μg
Storage
Store the lyophilized protein at -20°C to -80°C for long term.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
Manufacturers Research Area
Interleukin
Gene Symbol
IL-17A/CTLA-8
Protein Formulation
Lyophilized from a 0.22 μm filtered solution of 20 mM sodium citrate, 0.2 M NaCl, pH 4.5.
Protein Description
Recombinant Mouse IL-17A Protein is produced by Escherichia coli expression system. The target protein is expressed with sequence of Mouse IL-17A fused with polyhistidine tag at the C-terminus
Protein Bio Activity
Measured by its ability to inhibit IL-6 secretion in 3T3 cells. The ED50 for this effect is <1 ng/mL. The specific activity of recombinant mouse IL-17A is > 1 x 106 IU/mg.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
Listenpreis: 415,00 €
Preis: 415,00 €
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Lieferung vsl. bis 30.09.2025 

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