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Purified Anti-Mouse CD19 (1D3)

Purified Anti-Mouse CD19 (1D3)

€54.00

Excl. VAT

Item no.	70-0193-U100
Manufacturer	Tonbo Biosciences
Amount	100 ug
Category	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Antibodies By Cell Type Hematology Leukemia Lymphoma Flow Cytometry Immunohistochemistry Immunoprecipitation Primary Antibodies
Type	Antibody Monoclonal
Format	Purified
Applications	FC, IP, FA, IHCF, IHCP
Clone	1D3
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2a kappa
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Leu-12, B4
Available
Description	The 1D3 antibody reacts with mouse CD19, a 95 kDa glycoprotein which acts as a co-receptor, along with CD21 and CD81, in support of the functional B cell receptor (BCR). This complex provides antigen-specific recognition and subsequent activation of B cells to proliferate and differentiate into antibody-secreting cells (plasma cells) or memory B cells, which are crucial for secondary antigen encounter. CD19 is a lineage-differentiation marker, as its expression is detectable at the earliest B cell stages, through development, and is finally lost upon transition to mature plasma cells. The 1D3 antibody is widely used as a phenotypic marker for CD19 expression on B cells, as well as on dendritic cell subsets.
Alternative Names	Leu-12, B4
Gene ID	12478
Citations	Ghosn EEB, Yamamoto R, Hamanada S, Yang Y, Herzenberg LA, Nakauchi H, and Herzenberg LA. 2012. Proc. Natl. Acad. Sci. 109:5394-5398. (Flow cytometry) Raghavan S, Ostberg AK, Flach C-F, Ekman A, Blomquist M, Czerkinsky C, and Holmgren J. 2010. Infect. Immun. 78(10)4251-4260. (Immunohistochemistry - acetone fixed tissue) Togayachi A, Kozono Y, Ikehara Y, Ito H, et al. 2010. Proc. Natl. Acad. Sci. 107:11900-11905. (Immunoprecipitation) Poitrasson-Riviere M, Bienvenu B, Le Campion A, Becourt C, Martin B, and Lucas B. 2008. J. Immunol. 180:7294-7304. (Immunohistochemistry - paraffin embedded tissue) Lee Y, Haas KM, Gor DO, Ding X, Karp DR, Greenspan NS, Poe JC, and Tedder TF. 2005. J. Immunol. 175:8011-8023. (Immunoprecipitation) Bobbitt KR and Justement LB. 2000. J. Immunol. 165: 5588-5596. (in vitro stimulation, Immunoprecipitation)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Price: €54.00

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Delivery expected until 9/11/2025

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