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Purified Anti-Human CD45 (HI30)

Purified Anti-Human CD45 (HI30)

€40.00

Excl. VAT

Item no.	70-0459-U100
Manufacturer	Tonbo Biosciences
Amount	100 ug
Category	Oncology Neuroscience Neural Lineage Markers Metabolism Diabetes Antibodies By Cell Type Carcinoma Hematology Leukemia Flow Cytometry Immunohistochemistry Immunoprecipitation Western Blot Immunocytochemistry Primary Antibodies Progenitor Markers
Type	Antibody Monoclonal
Format	Purified
Applications	WB, FC, IP, ICC, FA, IHCF
Clone	HI30
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 kappa
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Leukocyte Common Antigen, LCA, Ly-5
Similar products	HI30
Available
Description	The HI30 antibody reacts with human CD45, one of the most abundant hematopoietic markers and one that is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, CD45RO and others. The HI30 antibody is widely used as a marker for human CD45 expression on T cells, B cells, monocytes, macrophages, and NK cells.
Alternative Names	Leukocyte Common Antigen, LCA, Ly-5
Gene ID	5788
Citations	Strowig T, Rongvaux A, Rathinam C, Takizawa H, Borsotti C, Philbrick W, Eynon EE, Manz MG, and Flavell RA. 2011. Proc. Natl. Acad. Sci. 108: 13218-13223. (Flow Cytometry) Kim M-H, Suh H-S, Si Q, Terman BE, and Lee SC. 2006. J. Virol. 80: 62-72. (in vitro blocking, Western Blot) Zhang M and Varki A. 2004. Glycobiology. 14: 939-949. (Immunoprecipitation) Gelbmann CM, Leeb SN, Vogl D, Maendel M, Herfarth H, Scholmerich J, Falk W, and Rogler G. 2003. Gut. 52:1448-1456. (Immunocytochemistry) Yamada T, Zhu D, Saxon A, and Zhang K. 2002. J. Biol. Chem. 277(32): 28830-28835. (in vitro blocking) Esser MT, Graham DR, Coren LV, Trubey CM, Bess JW, Arthur LO, Ott DE, and Lifson JD. 2001. J. Virol. 75(13)6173-6182. (Western Blot) Goto E, Kohrogi H, Hirata N, Tsumori K, Hirosako S, Hamamoto J, Fujii K, Kawano O, and Ando M. 2000. Am. J. Respir. Cell Mol. Biol. 22: 405. (Immunohistochemistry - frozen tissue) Esser MT, Graham DR, Coren LV, Trubey CM, Bess JW, Arthur LO, Ott DE, and Lifson JD. 2001. J. Virol. 75(13)6173-6182. (Western Blot)
Cross Reactivity	Chimpanzee

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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