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PE Anti-Human CD178 (Fas ligand) (NOK-1)

PE Anti-Human CD178 (Fas ligand) (NOK-1)

€63.00

Excl. VAT

Item no.	50-9919-T025
Manufacturer	Tonbo Biosciences
Amount	25 tests
Category	Oncology Metabolism Cholesterol & Lipid Metabolism Antibodies By Cell Type Carcinoma Cell Biology Cell Status Apoptosis Enzymes Fatty Acid Synthesis Primary Antibodies
Type	Antibody
Clone	NOK-1
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 kappa
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	NOK-1
Available
Description	The NOK-1 antibody reacts with human CD178 (Fas ligand) in both membrane bound and soluble forms. Fas ligand is a 40 kDa transmembrane glycoprotein, a member of the TNF family, and is expressed by activated T and NK cells, neutrophils, and monocytes. Interactions between CD178 (Fas ligand) and CD95 (Fas) induce a program of apoptosis and play a key role in immune regulation and homeostasis. The extracellular domain of human CD178 can be cleaved from the surface by matrix metalloproteinases (MMPs) resulting in a 26 kDa soluble protein.
Alternative Names	CD95L, Fas ligand, FasL
Gene ID	356
Citations	Tanaka M, Suda T, Takahashi T, and Nagata S. 1995. EMBO J. 14(6):1129-1135. Kayagaki N, Kawasaki A, Ebata T, Ohmoto H, Ikeda S, Inoue S, Yoshino K, Okumura K, and Yagita H. 1995. J Exp Med. 182(6):1777-1783. Suda T, Hashimoto H, Tanaka M, Ochi T, Nagata S. 1997. J Exp Med. 186(12):2045-2050. Ehrenschwender M, Wajant H. 2009. Adv Exp Med Biol. 647:64-93.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25 tests

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Delivery expected until 9/11/2025

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