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CLOZAPINE N-OXIDE

CLOZAPINE N-OXIDE

€33.00

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Item no.	TMO-T4494-2mg
Manufacturer	TargetMol
CASRN	34233-69-7
Amount	2mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,98
Citations	1. Dain, J.G., et al. Biotransformation of clozapine in humans. Drug Metabolism and Disposition 25(5), 603-609 (1997).
Smiles	C[N+]1([O-])CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Available
Short Description	Clozapine N-oxide is a major metabolite of clozapine that can be detected in the earliest excretion time interval after clozapine administration [1]. It is produced by the action of cytochrome P450 (CYP) isoforms CYP1A2 and CYP3A4, whose activities, in turn, can be affected by drugs and disease [2]. Clozapine N-oxide is normally biologically inactive. However, it can be used in designer receptor exclusively activated by designer drugs, also known as DREADDs, technology to modulate synthetic receptors in vivo [3].
Shipping	cool pack
Storage	-20°
Molecular Weight	342, 82
Pathway	Neuroscience\|\|\|Metabolism\|\|\|GPCR/G Protein
Target	5-HT Receptor\|\|\|Drug Metabolite\|\|\|AChR\|\|\|Dopamine Receptor

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Amount: 2mg

Listprice: €33.00

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Delivery expected until 8/21/2025

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