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Gilteritinib

Gilteritinib

€51.00

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Item no.	TMO-T4409-2mg
Manufacturer	TargetMol
CASRN	1254053-43-4
Amount	2mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,9775
Citations	1.Mori M,etal.Gilteritinib, a FLT3/AXL inhibitor, shows antileukemic activity in mouse models of FLT3 mutated acute myeloid leukemia.Invest New Drugs. 2017 Oct;35(5):556-565.
Smiles	CN1CCN(CC1)C2CCN(CC2)c3ccc(cc3OC)Nc5nc(NC4CCOCC4)c(CC)nc5C(N)=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	FLT;TAM Receptor, ASP2215
Available
Short Description	Gilteritinib is a potent inhibitor at the FMS-related tyrosine kinase 3 (FLT3) and AXL tyrosine kinase receptors (IC50 = 0.29 nM and <1 nM, respectively). In preClinicalal studies, gilteritinib showed strong antileukemic and antitumor effects. Gilteritinib is currently in several Phase 3 Clinicalal trials for acute myeloid leukemia.
Shipping	cool pack
Storage	-20°
Target names or alias	ASP2215
Molecular Weight	552, 72
Pathway	Tyrosine Kinase/Adaptors\|\|\|Angiogenesis
Target	TAM Receptor\|\|\|FLT\|\|\|c-Kit

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 2mg

Listprice: €51.00

Price: €51.00

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Delivery expected until 9/11/2025

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