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AST 487

AST 487

€34.00

Excl. VAT

Item no.	TMO-T4053-1mg
Manufacturer	TargetMol
CASRN	630124-46-8
Amount	1mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,9956
Citations	1. Akeno-Stuart N, et al. The RET Kinase Inhibitor NVP-AST487 Blocks Growth and Calcitonin Gene Expression through Distinct Mechanisms in Medullary Thyroid Cancer Cells. Cancer Res. 2007 Jul 15;67(14):6956-64.
Smiles	CNc1cc(Oc2ccc(NC(=O)Nc3ccc(CN4CCN(CC)CC4)c(C(F)(F)F)c3)cc2)ncn1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	NVP-AST 487
Available
Short Description	AST 487 is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3.
Shipping	cool pack
Storage	-20°
Target names or alias	NVP-AST 487
Molecular Weight	529, 56
Pathway	Apoptosis\|\|\|Tyrosine Kinase/Adaptors\|\|\|Angiogenesis\|\|\|Cytoskeletal Signaling
Target	c-RET\|\|\|VEGFR\|\|\|FLT\|\|\|Bcr-Abl\|\|\|c-Kit

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1mg

Listprice: €34.00

Price: €34.00

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Delivery expected until 9/4/2025

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