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Cediranib

Cediranib

€38.00

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Item no.	TMO-T2500-2mg
Manufacturer	TargetMol
CASRN	288383-20-0
Amount	2mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,99
Citations	1. Wedge SR, et al. Y Res. 2005 May 15; 65(10):4389-400.
Smiles	Cc1cc2c([nH]1)ccc(c2F)Oc1ncnc2cc(c(cc12)OC)OCCCN1CCCC1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	AZD2171 , NSC-732208
Available
Short Description	Cediranib (AZD2171) is a highly potent (IC50 < 1 nmol/L) ATP-competitive inhibitor of recombinant KDR tyrosine kinase in vitro, also inhibits Flt1/4 (IC50: 5 nM/≤3 nM), similar activity against PDGFRβ and c-Kit, selective more for VEGFR than PDGFR-α (36-fold), CSF-1R (110-fold), and Flt3 (1000-fold) in HUVEC cells.
Shipping	cool pack
Storage	-20°
Target names or alias	AZD2171 , NSC-732208
Molecular Weight	450, 51
Pathway	Autophagy\|\|\|Tyrosine Kinase/Adaptors\|\|\|Angiogenesis
Target	VEGFR\|\|\|Autophagy\|\|\|PDGFR\|\|\|c-Kit\|\|\|FLT

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 2mg

Listprice: €38.00

Price: €38.00

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Delivery expected until 9/4/2025

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