Anti-NIN antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Q8N4C6

This gene encodes one of the proteins important for centrosomal function. This protein is important for positioning and anchoring the microtubules minus-ends in epithelial cells. Localization of this protein to the centrosome requires three leucine zippers in the central coiled-coil domain. Multiple alternatively spliced transcript variants that encode different isoforms have been reported.

NIN

Rabbit polyclonal against NIN

Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Centriole
Component Of The Core Centrosome
Arranged In A Tubular Conformation With An Open And A Closed End Within The Centrosome
In The Mother Centrosome
It Localizes At Both Ends Of The Centrosome Tube
Including The Site Of Centrosome Duplication
While In The Daughter Centrosome It Is Present Only At The Closed End
Requires Pcm1 For Centrosome Localization
Localizes To The Subdistal Appendage Region Of The Centriole In A Dctn1-Dependent Manner
Isoform 6: Cytoplasm
Seems To Have A Dominant-Negative Effect On Localization Of Other Isoforms
Promoting Their Dissociation From The Centrosome

WB 1:500-1:2000

Ninein
Hninein
Glycogen Synthase Kinase 3 Beta-Interacting Protein
Gsk3b-Interacting Protein

NIN_HUMAN