Anti-SorLA antibody

Monoclonal

Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol.

Q92673

Mouse monoclonal to SorLA.

SORL1

Mouse monoclonal against SorLA

Golgi Apparatus Membrane
Single-Pass Type I Membrane Protein
Golgi Apparatus
Trans-Golgi Network Membrane
Endosome Membrane
Early Endosome Membrane
Recycling Endosome Membrane
Endoplasmic Reticulum Membrane
Endosome
Multivesicular Body Membrane
Cell Membrane
Cytoplasmic Vesicle
Secretory Vesicle Membrane
Secreted
Mostly Intracellular
Predominantly In The Trans-Golgi Network (Tgn) And In Endosome
As Well As In Endosome-To-Tgn Retrograde Vesicles
Found At Low Levels On The Plasma Membrane
At The Cell Surface
Partially Subjected To Proteolytic Shedding That Releases The Ectodomain (Also Called Soluble Sorla
Sollr11 Or Slr11) In The Extracellular Milieu
The Shedding May Be Catalyzed By Adam17/Tace
Following Shedding
Psen1/Presenilin-1 Cleaves The Remaining Transmembrane Fragment And Catalyzes The Release Of A C-Terminal Fragment In The Cytosol And Of A Soluble N-Terminal Beta Fragment In The Extracellular Milieu
The C-Terminal Cytosolic Fragment Localizes To The Nucleus
The Full-Length Protein Undergoes Partial Clathrin-Dependent Endocytosis Guided By Clathrin Adapter Protein 2 (Ap-2)

Anti-Sortilin-Related Receptor antibody
Anti-Low-Density Lipoprotein Receptor Relative With 11 Ligand-Binding Repeats antibody
Anti-Ldlr Relative With 11 Ligand-Binding Repeats antibody
Anti-Lr11 antibody
Anti-Sorla-1 antibody
Anti-Sorting Protein-Related Receptor Containing Ldlr Class A Repeats antibody
Anti-Sorla antibody
Anti-SORL1 C11orf32 antibody

FOR RESEARCH USE ONLY (RUO).