Anti-CD11b antibody

Unconjugated

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Store at-20° C, and avoid repeat freeze-thaw cycles.

CD11b also known as integrin alpha-M is a protein encoded by the ITGAM gene which is approximately 127, 1 kDa. CD11b is localised to the cell membrane and is involved in the MAPK-Erk pathway, apoptotic pathways, ERK signalling and integrin pathway. CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. CD11b is predominantly expressed in monocytes and granulocytes. Mutations in the ITGAM gene result in systemic Lupus Erythematosus. STJ97613 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of CD11b protein.

ITGAM

Internal

Predominantly expressed in monocytes and granulocytes. Expressed in neutrophils (at protein level).

WB 1:500-1:2000
ELISA 1:10000

Integrin Alpha-M
Cd11 Antigen-Like Family Member B
Cr-3 Alpha Chain
Cell Surface Glycoprotein Mac-1 Subunit Alpha
Leukocyte Adhesion Receptor Mo1
Neutrophil Adherence Receptor
Cd Antigen Cd11b

ITAM_HUMAN