Anti-CD27 antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

P26842

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

CD27

Rabbit polyclonal against CD27

Membrane
Single-Pass Type I Membrane Protein

WB 1:500-1:2000

Cd27 Antigen
Cd27l Receptor
T-Cell Activation Antigen Cd27
T14
Tumor Necrosis Factor Receptor Superfamily Member 7
Cd Antigen Cd27

CD27_HUMAN