Anti-LC3A antibody

Unconjugated

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Store at-20° C, and avoid repeat freeze-thaw cycles.

LC3A is a protein encoded by the MAP1LC3A gene which is approximately 14, 3 kD. LC3A is localised to the cytoplasm, cytoskeleton and autophagosome. It is involved in pathways such as the autophagy pathway, pink/parkin mediated mitophagy, ferroptosis, cellular senescence and pathways affecting insulin-like growth factor-Akt signalling. MAP1A and MAP1B fall under the LC3A protein. They are microtubule-associated proteins that mediate the physical interactions between microtubules and components of the cytoskeleton. LC3A is most abundant in heart, brain, liver, skeletal muscle and testis but absent in thymus and peripheral blood leukocytes. Mutations in the LC3A gene may result in Nasu-Hakola disease, lacrimal gland adenocarcinoma and leber congenital amaurosis. STJ97755 was developed from clone 5G10. It was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. The antibody detects endogenous levels of LC3A.

MAP1LC3A

Mouse monoclonal against LC3A

Cytoplasm
Cytoskeleton
Endomembrane System
Lipid-Anchor
Cytoplasmic Vesicle
Autophagosome Membrane
Autophagosome
Lc3-Ii Binds To The Autophagic Membranes

Anti-Microtubule-Associated Proteins 1a/1b Light Chain 3a antibody
Anti-Autophagy-Related Protein Lc3 A antibody
Anti-Autophagy-Related Ubiquitin-Like Modifier Lc3 A antibody
Anti-Map1 Light Chain 3-Like Protein 1 antibody
Anti-Map1a/Map1b Light Chain 3 A antibody
Anti-Map1a/Map1b Lc3 A antibody
Anti-Microtubule-Associated Protein 1 Light Chain 3 Alpha antibody
Anti-MAP1LC3A antibody

FOR RESEARCH USE ONLY (RUO).