Anti-Phospho-NF2 (S10) antibody

Polyclonal

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

P35240

1 mg/ml

4771

Synthesized peptide derived from human NF2 around the phosphorylation site of S10.

Rabbit polyclonal against Phospho-NF2 (S10)

Isoform 1: Cell Projection
Filopodium Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Cell Projection
Ruffle Membrane
Nucleus
In A Fibroblastic Cell Line
Isoform 1 Is Found Homogeneously Distributed Over The Entire Cell
With A Particularly Strong Staining In Ruffling Membranes And Filopodia
Colocalizes With Mpp1 In Non-Myelin-Forming Schwann Cells
Binds With Dcaf1 In The Nucleus
The Intramolecular Association Of The Ferm Domain With The C-Terminal Tail Promotes Nuclear Accumulation
The Unphosphorylated Form Accumulates Predominantly In The Nucleus While The Phosphorylated Form Is Largely Confined To The Non-Nuclear Fractions
Isoform 7: Cytoplasm
Perinuclear Region
Cytoplasmic Granule
Observed In Cytoplasmic Granules Concentrated In A Perinuclear Location
Isoform 7 Is Absent From Ruffling Membranes And Filopodia
Isoform 9: Cytoplasm
Isoform 9 Is Absent From Ruffling Membranes And Filopodia
Isoform 10: Nucleus
Cytoplasm
Cytoskeleton
Isoform 10 Is Found Homogeneously Distributed Over The Entire Cell

WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:5000

Merlin
Moesin-Ezrin-Radixin-Like Protein
Neurofibromin-2
Schwannomerlin
Schwannomin

MERL_HUMAN