Anti-PLAUR antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Q03405

This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.

PLAUR

Rabbit polyclonal against PLAUR

Cell Membrane
Cell Projection
Invadopodium Membrane
Colocalized With Fap (Seprase) Preferentially At The Cell Surface Of Invadopodia Membrane In A Cytoskeleton-
Integrin-And Vitronectin-Dependent Manner
Isoform 1: Cell Membrane
Lipid-Anchor
Gpi-Anchor
Isoform 2: Secreted

WB 1:500-1:2000

Urokinase Plasminogen Activator Surface Receptor
U-Par
Upar
Monocyte Activation Antigen Mo3
Cd Antigen Cd87

UPAR_HUMAN