Anti-CDK9 antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

P50750

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.

CDK9

Rabbit polyclonal against CDK9

Nucleus
Cytoplasm
Pml Body
Accumulates On Chromatin In Response To Replication Stress
Complexed With Ccnt1 In Nuclear Speckles
But Uncomplexed Form In The Cytoplasm
The Translocation From Nucleus To Cytoplasm Is Xpo1/Crm1-Dependent
Associates With Pml Body When Acetylated

WB 1:500-1:1000 IHC 1:50-1:100

Cyclin-Dependent Kinase 9
C-2k
Cell Division Cycle 2-Like Protein Kinase 4
Cell Division Protein Kinase 9
Serine/Threonine-Protein Kinase Pitalre
Tat-Associated Kinase Complex Catalytic Subunit

CDK9_HUMAN