Anti-RRM2B antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Q7LG56

This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.

RRM2B

Rabbit polyclonal against RRM2B

Cytoplasm
Nucleus
Translocates From Cytoplasm To Nucleus In Response To Dna Damage

WB 1:500-1:2000 IF 1:50-1:100

Ribonucleoside-Diphosphate Reductase Subunit M2 B
Tp53-Inducible Ribonucleotide Reductase M2 B
P53-Inducible Ribonucleotide Reductase Small Subunit 2-Like Protein
P53r2

RIR2B_HUMAN