Comparison

Human DPP4 / DPPIV / CD26 Protein (Fc Tag) European Partner

Item no. 10688-H01H-20
Manufacturer Sino Biological
Amount 20ug
Category
Type Proteins
Format Human Cell
Specific against Human (Homo sapiens)
Host Human
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias ADABP, ADCP2, CD26, DPPIV, TP103
Similar products DPP4
Available
Molecule
DPP4
Synonym
ADABP, ADCP2, CD26, DPPIV, TP103
Storage
Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Protein Construction
A DNA sequence encoding the extracellular domain (Asn 29-Pro 766) of the mature form of human DPPIV (NP_001926.2) was expressed with the fused Fc region of human IgG1 at the N-terminus.
Expressed Host
Human Cells
Purity
> 95 % as determined by SDS-PAGE
Bio-Activity
1. Measured by its ability to bind recombinant Cynomolgus CXCL12 in a functional ELISA.
2. Measured by its ability to bind recombinant Human SDF1b in a functional ELISA.
3. Using the Octet RED System, the affinity constant (Kd) of human Fc-DPPIV (Cat: 10688-H01H) bound to Spike (HCoV-EMC/2012) (Cat: 40071-V31B) was 11 nM.
4. Using the Octet RED System, the affinity constant (Kd) of human Fc-DPPIV (Cat: 10688-H01H) bound to Spike (HCoV-EMC/2012) (Cat: 40071-V05B) was 32 nM.
5. Using the Octet RED System, the affinity constant (Kd) of human Fc-DPPIV (Cat: 10688-H01H) bound to Spike (HCoV-EMC/2012) (ECD, aa 1-1297) (Cat: 40069-V08B) was 43 nM.
6. Using the Octet RED System, the affinity constant (Kd) of human Fc-DPPIV (Cat: 10688-H01H) bound to Spike-His (aa 1-760) (Cat: 40021-V08H) was 12 nM.
Endotoxin
< 1.0 EU per ug of the protein as determined by the LAL method
Predicted N Terminal
Glu 20
Molecule Mass
The recombinant human Fc/DPPIV is a disulfide-linked homodimeric protein.The reduced monomer consists of 975 amino acids and has a predicted molecular mass of 112 kDa. As a result of glycosylation, the apparent molecular mass of rhFc/DPPIV monomer is approximately 120-130 kDa in SDS-PAGE under reducing conditions.
Formulation
Lyophilized from sterile PBS, pH 7.4
Accession
NP_001926.2
Amino acid sequence
Asn29-Pro766
TAG
N-human IgG1-Fc

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 20ug
Available: In stock
available

Delivery expected until 9/4/2025 

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