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Pepstatin Ammonium

Pepstatin Ammonium

€31.00

Excl. VAT

Item no.	HY-P0018B-5mg
Manufacturer	MedChem Express
Amount	5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	99.76
Formula	C34H66N6O9
Citations	Biol Pharm Bull. 2022 Feb 3. Adv Sci (Weinh). 2022 Oct 10;e2203831. Arch Biochem Biophys. 2023 May 22, 109646. Biochem Bioph Res Co. 2020 Sep 10;530(1):292-300. Cancer Lett. 2022 Mar 9;215629. Carbohydr Polym. 2023 Jul 17, 121208. Cell Death Dis. 2022 Dec 16;13(12):1048. Cell Rep. 2021 Nov 2;37(5):109931. Environ Sci Technol. 2017 Dec 5;51(23):13938-13948. Eur J Pharmacol. 2022 Feb 11;920:174823. FASEB J. 2022 Jan;36(1):e22121. Int J Oncol. 2019 Jul;55(1):331-339. J Virol. 2021 Sep 22;JVI0153721. J Virol. 2023 Oct 17:e0107523. Mol Med Rep. 2019 Jan;19(1):41-50. Pharmaceuticals. 2022, 15(12), 1509 Pharmacol Res. 2021 Dec 1;175:105985. Sci Adv. 2022 Nov 11;8(45):eabn6579. SSRN. 2023 Apr 10. Toxicol Appl Pharmacol. 2018 Oct 1;356:159-171. Int J Antimicrob Agents. 2019 Dec;54(6):814-819. [1]Umezawa H, et al. Pepstatin, a new pepsin inhibitor produced by Actinomycetes. J Antibiot (Tokyo). 1970 May;23(5):259-62. [2]Seelmeier S, et al. Human immunodeficiency virus has an aspartic-type protease that can be inhibited by pepstatin A. Proc Natl Acad Sci U S A. 1988 Sep;85(18):6612-6.
Smiles	CC(C[C@H](NC([C@@H](NC([C@@H](NC(CC(C)C)=O)C(C)C)=O)C(C)C)=O)[C@@H](O)CC(N[C@@H](C)C(N[C@@H](CC(C)C)[C@@H](O)CC(O)=O)=O)=O)C.N
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	Pepstatin A Ammonium
Available
Product Description	Pepstatin (Pepstatin A) Ammonium is a specific, orally active aspartic protease inhibitor produced by actinomycetes, with IC50s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease, respectively. Pepstatin Ammonium also inhibits HIV protease[1][2].
StorageTemperature	-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Shipping	Blue Ice
Manufacturers Applications	COVID-19-anti-virus
Molecular Weight	702.92
Clinical Information	No Development Reported
Solubility	DMSO : 25 mg/mL (ultrasonic)
Pathway	Anti-infection; Autophagy; Metabolic Enzyme/Protease
Manufacturers Product type	Peptides

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5 mg

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