TPE-MI

€758.00

Excl. VAT

Item no.	HY-143218-50mg
Manufacturer	MedChem Express
CASRN	1245606-71-6
Amount	50 mg
Category	Reagents & Chemicals Staining & Dyes
Type	Reagents
Specific against	other
Purity	98.54
Formula	C31H23NO2
Citations	[1]Chen MZ, et al. A thiol probe for measuring unfolded protein load and proteostasis in cells. Nat Commun. 2017;8(1):474. Published 2017 Sep 7. [2]Hu Q, et al. In Situ Monitored Vortex Fluidic-Mediated Protein Refolding/Unfolding Using an Aggregation-Induced Emission Bioprobe. Molecules. 2021;26(14):4273. Published 2021 Jul 14.
Smiles	O=C(C=C1)N(C2=CC=C(/C(C3=CC=CC=C3)=C(C4=CC=C(C)C=C4)/C5=CC=CC=C5)C=C2)C1=O
ECLASS 10.1	42051003
ECLASS 11.0	42051003
UNSPSC	12000000
Alias	Tetraphenylethene maleimide
Available
Product Description	TPE-MI (Tetraphenylethene maleimide) is a thiol probe for measuring unfolded protein load and proteostasis in cells. TPE-MI can report imbalances in proteostasis in induced pluripotent stem cell models of Huntington disease, as well as cells transfected with mutant Huntington exon 1 before the formation of visible aggregates. TPE-MI also detects protein damage following dihydroartemisinin research of the malaria parasitesPlasmodium falciparum [1][2].
StorageTemperature	4°C (Powder, protect from light)
Shipping	Room Temperature
Manufacturers Applications	Neuroscience-Neurodegeneration
Molecular Weight	441.52
Clinical Information	No Development Reported
Solubility	DMSO : 44.15 mg/mL (ultrasonic)
Isoform	Plasmodium
Pathway	Anti-infection; Neuronal Signaling
Manufacturers Product type	Dye Reagents

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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