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γ-Secretase modulator 4

γ-Secretase modulator 4

€9,829.00

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Item no.	HY-128581-100mg
Manufacturer	MedChem Express
CASRN	1420200-82-3
Amount	100 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Purity	99.47
Formula	C23H19FN4O2
Citations	[1]Bischoff FP, et al. Design and synthesis of a novel series of cyanoindole derivatives as potent γ-secretase modulators. Bioorg Med Chem Lett. 2019 Jul 15;29(14):1737-1745.
Smiles	N#CC1=C(OC)C2=C(C=C1)NC(C3=CN(CCO[C@H]4C5=CC=CC(F)=C5C)C4=N3)=C2
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Available
Product Description	γ-Secretase modulator 4 is a potent γ-secretase modulator, reduces the Aβ42 level with IC50s of 0.014 μM and 0.017 μM in human and mouse, respectively[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Neuroscience-Neurodegeneration
Molecular Weight	402.42
Clinical Information	No Development Reported
Solubility	DMSO : 100 mg/mL (ultrasonic)
Pathway	Neuronal Signaling; Stem Cell/Wnt
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 mg

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