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GNE-0749

GNE-0749

€14,521.00

Excl. VAT

Item no.	DCC-DC53043-100mg
Manufacturer	DCChemicals
Amount	100 mg
Category	Reagents & Chemicals Other Chemicals
Type	Chemicals
Specific against	other
Smiles	N(CCC(C)(C)C)C(NC1=CC(NC2C=CC3=C(C=2F)C(=O)N(C)C=N3)=C(C)C=C1F)=O
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Available
Molecule Weight	443, 5
Field of Application	GNE-0749 is a potent and selective pan-RAF inhibitor with Ki of 0.061 nM and <0.08 nM for CRAF and BRAF, respectively. Combinated with cobimetinib, GNE-0749 demonstrates synergistic pharmacodynamic effects in the KRAS mutant HCT116 tumor-bearing mice.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 mg

Listprice: €14,521.00

Price: €14,521.00

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Delivery expected until 9/25/2025

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