Biotinylated SARS-CoV-2 Spike RBD (L452R), His,Avitag (MALS verified)

Immobilized Human ACE2, Fc Tag (Cat. No. AC2-H5257) at 1 ?g/mL (100 ?L/well) can bind Biotinylated SARS-CoV-2 Spike RBD, His, Avitag (Cat. No. SPD-C82E3) with a linear range of 2-63 ng/mL (QC tested).

PBS, pH7.4

It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Arg 319 - Lys 537

28.3 kDa

Biotinylated SARS-CoV-2 Spike RBD (L452R), His, Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.