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Human SIGIRR Protein, Fc Tag (MALS verified)

Human SIGIRR Protein, Fc Tag (MALS verified)

€317.00

Excl. VAT

Item no.	SIR-H5255-100ug
Manufacturer	ACROBiosystems
Amount	100ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Powder
Specific against	Human (Homo sapiens)
Conjugate/Tag	Unconjugated
Purity	>95% as determined by SDS-PAGE.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Single Ig IL-1-related receptor,Single Ig IL-1R-related molecule,Single immunoglobulin domain-containing IL1R-related protein,Toll/interleukin-1 receptor 8,TIR8
Available
Buffer	PBS, pH7.4
Characteristics	This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 39.0 kDa. The protein migrates as 50-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Description	Single immunoglobulin IL-1-related receptor (SIGIRR), which is also known as Toll/interleukin-1 receptor 8, is a member of the interleukin-1 receptor (IL-1R) family. SIGIRR acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.
Endotoxin Level	Less than 1.0 EU per μg by the LAL method.
Exp Region	Met 1 - His 118
Expression System	HEK293
Molecular Weight	39.0 kDa
Molecule	SIGIRR
SDS-PAGE Legend	Human SIGIRR, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Shipping condition	RT
Storage	-20℃

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ug

Listprice: €317.00

Price: €317.00

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Delivery expected until 8/28/2025

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