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CD275 [B7-H2] non-lytic Recombinant Protein

CD275 [B7-H2] non-lytic Recombinant Protein

€678.00

Excl. VAT

Item no.	PRS-90-437-100ug
Manufacturer	ProSci
Amount	100 ug
Category	Neuroscience Neural Lineage Markers Metabolism Diabetes Glucose Homeostasis Molecular Targets for Neuroscience Targets for Rodent Neurosciences Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Lyophilized
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	B7-H2, ICOS Ligand, B7-like Protein Gl50, B7RP-1
Available
Applications	This recombinant proteins is for research use only.
Applications	This recombinant proteins is for research use only.
Buffer	Lyophilized from 0.2um-filtered solution in PBS. Reconstitute at 100 μ g/ml in sterile PBS.
Storage Conditions	Stable for at least 1 year after receipt when stored at -20˚ C. Working aliquots are stable for up to 3 months when stored at -20˚ C.
Disclaimer	Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Purity	≥98% (SDS-PAGE). Endotoxin level is less than 0.06EU/ μ g protein (LAL test; Lonza).
Background	Mouse CD275 (B7-H2) is a member of the growing B7 family of immune costimulatory proteins. CD275 has been identified as the ligand for ICOS, a member of the CD28 family of co-stimulatory receptors. Mouse CD275 is expressed on resting B cells and at low levels on monocytes. The CD275/ICOS interaction appears to play roles in T cell dependent B cell activation and Th differentiation.
Accession #	NP_056605
Ncbi Gene Id #	50723
Ncbi Official Symbol	Icosl
Ncbi Official Full Name	icos ligand
Ncbi Organism	Mus musculus
Swissprot #	P05231
Fusion Tag	Fc Tag
Sequence	The extracellular domain of mouse CD275 [B7-H2] (aa 48-279) is fused to the N-terminus of the Fc region of a mutant mouse IgG2a.
Biological Activity	Measured by its binding ability in a functional ELISA. Immobilized human ICOS at 1ug/ml (100ul/well) can bind biotinylated B7-H2 (mouse):Fc (mouse) (rec.) (non-lytic) with a linear range of 0.1-1.0ug/ml. Optimal dilutions should be determined by each laboratory for each application.
Protein Gi#	7657220

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

Listprice: €678.00

Price: €678.00

available

Delivery expected until 10/2/2025

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