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LIGHT Recombinant Protein

LIGHT Recombinant Protein

€314.00

Excl. VAT

Item no.	PRS-40-452-0.005mg
Manufacturer	ProSci
Amount	0.005 mg
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Peptides & Proteins Recombinant Proteins Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis
Type	Proteins Recombinant
Format	Lyophilized
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	LTg, HVEML, LIGHT, Ly113, HVEM-L, Light, Tumor necrosis factor ligand superfamily member 14
Available
Storage Conditions	The lyophilized LIGHT recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted LIGHT is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing LIGHT recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Disclaimer	This product is for research use only.
Purity	Greater than 98% by SDS-PAGE gel and HPLC analyses. Endotoxin level is less than 0.1 ng per μ g (1EU/μ g).
Background	LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTβ R, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD+8 tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT has the ability to active NFkB, to co-stimulate the activation of lymphocytes and to induce apoptosis in certain human tumor cells. Recombinant murine LIGHT is a 20.1 kDa protein containing 183 amino acid residues.
Accession #	NP_062291.1
Ncbi Gene Id #	50930
Ncbi Official Symbol	Tnfsf14
Ncbi Official Full Name	tumor necrosis factor (ligand) superfamily, member 14
Ncbi Organism	Mus musculus
Swissprot #	Q9QYH9
Sequence	MRLHQRLGDI VAHLPDGGKG SWEKLIQDQR SHQANPAAHL TGANASLIGI GGPLLWETRL GLAFLRGLTY HDGALVTMEP GYYYVYSKVQ LSGVGCPQGL ANGLPITHGL YKRTSRYPKE LELLVSRRSP CGRANSSRVW WDSSFLGGVV HLEAGEEVVV RVPGNRLVRP RDGTRSYFGA FMV
Protein Gi#	9507195
Peptide Sequence	MRLHQRLGDI VAHLPDGGKG SWEKLIQDQR SHQANPAAHL TGANASLIGI GGPLLWETRL GLAFLRGLTY HDGALVTMEP GYYYVYSKVQ LSGVGCPQGL ANGLPITHGL YKRTSRYPKE LELLVSRRSP CGRANSSRVW WDSSFLGGVV HLEAGEEVVV RVPGNRLVRP RDGTRSYFGA FMV

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.005 mg

Listprice: €314.00

Price: €314.00

available

Delivery expected until 10/2/2025

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