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SARS CoV-2 full length spike protein nanodisc complex

SARS CoV-2 full length spike protein nanodisc complex

€2,068.00

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Item no.	PRS-21-817-0.025mg
Manufacturer	ProSci
Amount	0.025 mg
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Liquid
Applications	ELISA
Specific against	other
Dry ice	Yes
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	SARS-CoV-2 (COVID-19) Spike Recombinant Protein: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Surface Glycoprotein, Spike protein
Available
Applications	This recombinant protein can be used for ELISA assays, Ligand binding assays (e.g. SPR), Biochemical and biophysical analyses. For research use only.
Applications	This recombinant protein can be used for ELISA assays, Ligand binding assays (e.g. SPR), Biochemical and biophysical analyses. For research use only.
Buffer	20 mM Hepes pH 7.5; 150 mM NaCl,
Storage Conditions	–80˚ C. Avoid freeze-thaw cycles
Disclaimer	Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Predicted Molecular Weight	1286 amino acids (including Rho1D4 tag and linker); 142114 Da
Purity	>98% as determined by SDS-PAGE, see Fig. 1 A and B. PureCube Rho1D4 Agarose.
Background	The coronavirus, also known as SARS-CoV-2, enters the cell by using its surface SPIKE. SPIKE is processed on the cell's surface by TMPRSS2, a serine protease. It then subsequently binds to ACE2 a cell surface receptor. The Native SPIKE protein is a trimer that is located in the coronavirus membrane. Therefore to get pure & native SPIKE the trimer needs to be kept intact. Our lab staff achieved this in three different ways: MSP nanodiscs, based on MSP proteins Detergent Mycelles, as you can see here Synthetic nanodiscs
1St Image Caption3	Figure 1: SDS Page of purified SPIKE protein in MSP1D1 nanodiscs. The band that represents the MSP protein can also be seen.
Concentration	batch dependent
Ncbi Gene Id #	43740568
Ncbi Official Symbol	S
Ncbi Official Full Name	surface glycoprotein
Ncbi Organism	Severe acute respiratory syndrome coronavirus 2
Swissprot #	P0DTC2
Fusion Tag	C-terminal Rho1D4
Sequence	Full-length sequence (aa 1 – 1273), furin cleavage site “RRAR” mutated to “GSAG”; C-terminal Rho1D4 tag fused with spacer “GSSG” to protein sequence
Biological Activity	not determined
Peptide Sequence	Full-length sequence (aa 1 – 1273), furin cleavage site “RRAR” mutated to “GSAG”; C-terminal Rho1D4 tag fused with spacer “GSSG” to protein sequence

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.025 mg

Listprice: €2,068.00

Price: €2,068.00

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Delivery expected until 10/2/2025

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