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LIGHT / TNFSF14 Recombinant Protein

LIGHT / TNFSF14 Recombinant Protein

€749.00

Excl. VAT

Item no.	PRS-11-456-0.1mg
Manufacturer	ProSci
Amount	0.1 mg
Category	Peptides & Proteins Recombinant Proteins Western Blot ELISA
Type	Proteins Recombinant
Format	Lyophilized
Applications	WB, ELISA
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CD258 antigen,CD258,HVEM-L,LIGHT,LTg,TNFSF14,TR2,HVEML
Available
Applications	This protein carries a mouse IgG2a Fc tag at the N-terminus. The protein has a calculated MW of 45.1 kDa. The protein migrates as 50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Applications	This protein carries a mouse IgG2a Fc tag at the N-terminus. The protein has a calculated MW of 45.1 kDa. The protein migrates as 50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Buffer	Tris with Glycine, Arginine and NaCl, pH7.5
Storage Conditions	Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Disclaimer	Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Predicted Molecular Weight	45.1 kDa
Purity	>95% as determined by SDS-PAGE.
Background	Tumor necrosis factor ligand superfamily member 14(LIGHT) is a tumor necrosis factor (TNF) superfamily ligand that regulates T cell immune responses by signaling through the herpes virus entry mediator (HVEM) and the lymphotoxin beta receptor (LTbetaR). LIGHT has emerged as a potent initiator of T cell co-stimulation signals effecting CTL-mediated tumor rejection, allograft rejection and graft versus host disease. Constitutive expression of LIGHT leads to tissue destruction and autoimmune-like disease syndromes.
1St Image Caption3	Human LIGHT, Mouse IgG2a Fc Tag, low endotoxin on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Background References 1	Mauri DN., et al. 1998, Immunity., 8, 21-30.
Background References 2	Granger SW., et al. 2003, Cytokine Growth Factor Rev., 14(3-4), 289-96.
Background References 3	Pasero C., et al. 2009, Curr Mol Med., 9(7), 911-27.
Accession #	NP 003798.2
Ncbi Gene Id #	8740
Ncbi Official Symbol	TNFSF14
Ncbi Official Full Name	TNF superfamily member 14
Ncbi Organism	Homo sapiens
Swissprot #	O43557
Fusion Tag	Mouse IgG Fc Tag
Sequence	Asp 74 - Val 240

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

Listprice: €749.00

Price: €749.00

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Delivery expected until 10/2/2025

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