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HCoV-HKU1(isolate N5) S1 Recombinant Protein

HCoV-HKU1(isolate N5) S1 Recombinant Protein

€788.00

Excl. VAT

Item no.	PRS-11-195-0.1mg
Manufacturer	ProSci
Amount	0.1 mg
Category	Infectious Diseases Viral Infections Coronavirus (COVID-19) Peptides & Proteins Recombinant Proteins Western Blot
Type	Proteins Recombinant
Format	Lyophilized
Applications	WB
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Spike,S1 protein,Spike glycoprotein Subunit1,S glycoprotein Subunit1,Spike protein S1,COVID-19
Available
Applications	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 85.7 kDa. The protein migrates as 110-130 kDa under reducing (R) condition (SDS-PAGE) due to Glycosylation.
Applications	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 85.7 kDa. The protein migrates as 110-130 kDa under reducing (R) condition (SDS-PAGE) due to Glycosylation.
Buffer	PBS, pH7.4
Storage Conditions	Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Disclaimer	Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Predicted Molecular Weight	85.7 kDa
Purity	>90% as determined by SDS-PAGE.
Background	It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
1St Image Caption3	HCoV-HKU1(isolate N5) S1 protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Background References 1	Wan Y, et al. J Virol. 2020. pii: JVI.00127-20.
Background References 2	Benvenuto D, et al. J Med Virol. 2020.
Background References 3	Chang CY, et al. AMB Express. 2020. 10(1):20.
Fusion Tag	His Tag
Sequence	Ala 13 - Arg 756

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

Listprice: €788.00

Price: €788.00

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Delivery expected until 9/4/2025

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