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SARS-CoV-2 (COVID-19) NSP7&NSP8 Protein, His Tag

SARS-CoV-2 (COVID-19) NSP7&NSP8 Protein, His Tag

€2,965.00

Excl. VAT

Item no.	NS8-C5125-1mg
Manufacturer	ACROBiosystems
Amount	1mg
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Liquid
Specific against	SARS-CoV-2
Conjugate/Tag	His
Purity	>95% as determined by SDS-PAGE.
Dry ice	Yes
Citations	(1) Krichel B, et al. Biochem J. 2020. 477(5):1009-1019. (2) Kirchdoerfer RN, et al. Nat Commun. 2019. 10(1):2342.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	NSP7 & NSP8,nsp7 & nsp8,COVID-19
Available
Buffer	PBS, pH7.4
Characteristics	This protein carries a polyhistidine tag. The protein has a calculated MW of 32.1 kDa. The protein migrates as 28-32 kDa under reducing (R) condition (SDS-PAGE).
Description	During the formation of the coronaviral replication/transcription complex, essential steps include processing of the conserved polyprotein nsp7-10 region by the main protease Mpro and subsequent complex formation of the released nsp's. Upon infecting host cells, coronaviruses assemble a multi-subunit RNA-synthesis complex of viral non-structural proteins (nsp) responsible for the replication and transcription of the viral genome. non-structural proteins 7 (NSP7) forms a hexadecamer with nsp8 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers.
Endotoxin Level	Less than 1.0 EU per ug by the LAL method.
Exp Region	Ser 1 - Gln 83 (NSP7) & Ala 1 - Gln 198 (NSP8)
Molecular Weight	32.1 kDa
Molecule	NSP7 & NSP8
Shipping condition	Liquid, -70CDry ice
Storage	-70C

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.